Projects

Personalized therapeutic targeting of specific tumor vulnerabilities

Personalized therapeutic targeting of specific tumor vulnerabilities

One of the major clinical challenges in these tumors is to identify tumor specific vulnerabilities that can be therapeutically targeted. The lab focuses on understanding the underlying genetic reasons/ mutations that cause such therapeutic vulnerabilities.

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Personalized therapeutic targeting of specific tumor vulnerabilities

One of the major clinical challenges in these tumors is to identify tumor specific vulnerabilities that can be therapeutically targeted. The lab focuses on understanding the underlying genetic reasons/ mutations that cause such therapeutic vulnerabilities.

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DNA circularization as an oncogenic driver of genomic instability in pediatric cancer

DNA circularization as an oncogenic driver of genomic instability in pediatric cancer

In recent years it has become apparent that the genomes of pediatric cancers are more complex than previously anticipated. One phenomenon observed in pediatric cancers is the circularization of DNA.

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DNA circularization as an oncogenic driver of genomic instability in pediatric cancer

In recent years it has become apparent that the genomes of pediatric cancers are more complex than previously anticipated. One phenomenon observed in pediatric cancers is the circularization of DNA.

More Details