Functional proteomics and molecular pharmacology of pediatric cancers

Functional genomicsof pediatric cancers

Experimental and Clinical Research Center (ECRC)
MDC and Charité Berlin
Research focus of the Henssen Lab

Projects

Personalized therapeutic targeting of specific tumor vulnerabilities

Personalized therapeutic targeting of specific tumor vulnerabilities

One of the major clinical challenges in these tumors is to identify tumor specific vulnerabilities that can be therapeutically targeted. The lab focuses on understanding the underlying genetic reasons/ mutations that cause such therapeutic vulnerabilities.

DNA circularization as an oncogenic driver of genomic instability in pediatric cancer

DNA circularization as an oncogenic driver of genomic instability in pediatric cancer

In recent years it has become apparent that the genomes of pediatric cancers are more complex than previously anticipated. One phenomenon observed in pediatric cancers is the circularization of DNA.

Emmy Noether Programm Berliner Berlin Institute of Health Deutsche Krebshilfe Charite Clinical Scientist Charite Wilhelm Sander-Stiftung
Emmy Noether Programm Berliner Berlin Institute of Health Deutsche Krebshilfe Charite Clinical Scientist Charite Wilhelm Sander-Stiftung
We Are Henssen Research Group

Meet Two Of Us

Our group of physicians and scientists in the Department of Pediatric Hematology and Oncology at the Charité Universitätsmedizin is particularly interested in understanding how refractory neuroblastoma and rhabdomyosarcoma are formed. Our research is focused on the phenomenon of genomic plasticity and its resultant therapeutically targetable vulnerabilities.

Check our Team
Rocío Chamorro González

Rocío Chamorro GonzálezPhD student

Heathcliff Dorado García

Heathcliff Dorado GarcíaM.Sc. is a biotechnologist and cancer biologist

Papers

Our Publications